I did not have an adverse reaction, but there have been a few times while getting work done in my mouth that the doctor has not been able to get my mouth completely numb despite using a lot of Novocaine, after the fact I learned that this could have been the result of the fact that I was using stimulants at the time and did not discuss this with my dentist out of fear of being refused treatment, stigma, discrimination or judgement.  I also learned that using stimulants while also being administered Novocaine can be deadly, so I consider myself very lucky that nothing scary happened and will not ever take chances like that again.  Although I am not currently using stimulants, and do not plan to in the near future, from that incident forward I plan to be transparent with my medical provider about substances that I am using whether or not they are prescribed to me. 