Showering on 6/15/2011, I felt something "snap" inside my head and nearly dropped to my knees, screaming aloud "What was that?!".  Within minutes, I had dark feelings of utter futility of life as I'd never before experienced. Subsequently my pain clinic sensed something was very wrong, gave me an antidepressant, and referred me to a psychiatrist who diagnosed depression and prescribed medication.  Under her care, I eventually recovered.
In late 2019, I had pneumonia for the first time in my life, followed by thrush.  I fully believe this was due to my lungs being weakened by pneumothorax.  At the end of this illness, I started having precipitous anxiety attacks which I'd never before experienced.  I sought psychiatric help but got no relief.  Eventually, my pain doc saw me in misery and suggested hydroxyzine, which sometimes works miraculously where benzos had no effect.  However, I've since traced my sudden anxiety response to Suboxone use.  About half of the time, a Suboxone dose will trigger an anxiety attack within 3 minutes.  This is a new side effect.  Suboxone also lost much of its efficacy and sometimes makes pain worse instead of better.