Have had challenges with initial RLS medication I took from 2002 to 2009; dopamine agonists called requip/mirapex
Medication was new to the market in 2002 for RLS.
The first actual medication on the Market for severe Restless legs syndrome
Side effects included weight gain, severe cravings for sugar, high sex drive, OCD behaviors that never occurred before this long term medication I took for 8 years. Lost 25 lbs the first month off the medication.
All troublesome side effects that led to having seven ECT (electro-convulsive therapy) treatments, I stopped the ECT treatments and was put on klonopin, which I’ve been on ever sense. It helped with the lingering anxiety and was a secondary treatment for RLS.
For the primary medication for RLS:
2002-2009 - Requip/Mirapex - dopamine agonist 
2009-2011 - hydrocodone
2012 - present — suboxone/ zubsolv  

